A Facile One-Pot Synthesis of Functionalized N-Hydroxypyrrole Mediated by Vinyl-Triphenylphosphonium Salt

نویسندگان

  • Issa Yavari Department of Chemistry, Tarbiat Modares University, P.O. Box 14155-4838, Tehran, I.R. IRAN
  • Marjaneh Samadi Zadeh Department of Chemistry, Islamic Azad University, Science and Research Campus, Tehran, I.R. IRAN
  • Sakineh Asghari Department of Chemistry, Tarbiat Modarres University, P.O. Box 14155-4838, Tehran, I.R. IRAN
چکیده مقاله:

Protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular Wittig reaction to produce dalkyl 4-phenyl-N-hydroxypyrrole-2,3-dicarboxylates in moderate yields.

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a facile one-pot synthesis of functionalized n-hydroxypyrrole mediated by vinyl-triphenylphosphonium salt

protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular wittig reaction to produce dalkyl 4-phenyl-n-hydroxypyrrole-2,3-dicarboxylates in moderate yields.

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عنوان ژورنال

دوره 17  شماره 1

صفحات  38- 41

تاریخ انتشار 1998-06-01

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